CD147/EMMPRIN/Neurothelin [clone 8D6], anti-human

Description: This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.Localization: membraneDilution: 50-200Positive Control: colon ca, placentaHIER: citrate pH6.0Status: RUO