CD15 (clone HI98), anti-human

CD15 (clone HI98), anti-human

€323.00
In stock
SKU
250948
Catalog Nr.: 250948
Size: 0.1 mg
Isotype: mouse IgM
Applications: E, FC, IHC
Protein Family: Cellular Antigens, Glycosyltransferases

Pathway and Disease: Glycan Biosynthesis and Metabolism, Immune System

Description:
The CD15 (HI98) antibody recognizes a 220-kDa carbohydrate antigen–Lacto–N–fucopentaose III, also called Lewis X, X-hapten, and SSEA-I. CD15 antigen is expressed on mature granulocytes (strongly), monocytes (weakly), immature bone marrow cells of myelomonocytic lineage, peripheral blood T lymphocytes (weakly), and some T-cells. CD15 antigen is also expressed on leukemia cells of myelomonocytic origin, Langerhans cells, a variety of carcinoma cells (preferentially adenocarcinomas), and occasionally on lymphocytic leukemia cells. CD15 is absent from B lymphocytes, erythrocytes and platelets. A soluble form of CD15 exists in serum (plasma) besides a membrane form. CD15 antigen plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.

Alternate Names: Alpha-(1, 3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase, CD15, FUT4, ELFT, FCT3A

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen and formalin-fixed paraffin sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500

Accession No.: P22083, NP_002024

Format: Each vial contains 0.1 mg IgM in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by hydroxyapatite chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Shen DC. et al. 1989. J. Hematol, 10(7): 350
Guan Q. et al. 1993. Tissue Antigens. 42(4): 365.
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