CD150 (SLAMF1) polyclonal, anti-human, mouse, rat
€347.00
In stock
SKU
254448
Catalog Nr.: 254448
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
Alternate Names: Signaling lymphocytic activation molecule family member 1, CD150, CDw150, IPO-3, SLAM
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_003028
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human SLAMF1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
Alternate Names: Signaling lymphocytic activation molecule family member 1, CD150, CDw150, IPO-3, SLAM
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_003028
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human SLAMF1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review