CD180 polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS61344
Background:
RP105 is a mouse B-cell surface molecule that transmits a growth-promoting signal and is implicated in the life/death decision of B cells. RP105 has tandem repeats of a leucine-rich motif in its extracellular domain that are presumed to be involved in protein-protein interactions. The amino acid sequence of human RP105 is highly homologous to that of mouse RP105; human RP105 shares 74% identity with the mouse protein, as well as the leucine-rich motif. Surface expression of RP105 is enhanced in the presence of MD1, although this expression is restricted to CD19-positive B cells. RP105 demonstrates predominant expression on mature B cells in mantle zones; very little expression is observed in germinal centers.
Alternative Name:
CD180 antigen, Lymphocyte antigen 64, Radioprotective 105 kDa protein, CD_antigen: CD180, LY64, RP105
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: CD180 polyclonal antibody detects endogenous levels of CD180 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CD180 .
MW: ~ 74 kD
Swis Prot.: Q99467
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RP105 is a mouse B-cell surface molecule that transmits a growth-promoting signal and is implicated in the life/death decision of B cells. RP105 has tandem repeats of a leucine-rich motif in its extracellular domain that are presumed to be involved in protein-protein interactions. The amino acid sequence of human RP105 is highly homologous to that of mouse RP105; human RP105 shares 74% identity with the mouse protein, as well as the leucine-rich motif. Surface expression of RP105 is enhanced in the presence of MD1, although this expression is restricted to CD19-positive B cells. RP105 demonstrates predominant expression on mature B cells in mantle zones; very little expression is observed in germinal centers.
Alternative Name:
CD180 antigen, Lymphocyte antigen 64, Radioprotective 105 kDa protein, CD_antigen: CD180, LY64, RP105
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: CD180 polyclonal antibody detects endogenous levels of CD180 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CD180 .
MW: ~ 74 kD
Swis Prot.: Q99467
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review