CD19 (clone 2E2), anti-human
€394.00
In stock
SKU
252999
Catalog Nr.: 252999
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, IF, FC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, IF, FC
Protein Family: Cellular Antigens, Receptors and Channels
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation.
Alternate Names: B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, Leu-12, CD19 antigen, CD19
Application Notes: E: 1:10000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P15391
Antigen: Purified recombinant fragment of human CD19 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation.
Alternate Names: B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, Leu-12, CD19 antigen, CD19
Application Notes: E: 1:10000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P15391
Antigen: Purified recombinant fragment of human CD19 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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