CD19 (clone ), anti-human, mouse
€428.00
In stock
SKU
MB9024
Background:
CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is selectively expressed on the cell surface of B-lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. CD19 forms functional complexes with B-lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B-cell development.
Alternative Name:
B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12,
Application Dilution: WB: 1:500, IHC: 1:100-1:200, FC: 1:100-1:200
Specificity: This antibody detects endogenous levels of CD19 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of CD19.
MW: ~ 61, 95 kDa
Swis Prot.: P15391
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG1. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is selectively expressed on the cell surface of B-lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. CD19 forms functional complexes with B-lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B-cell development.
Alternative Name:
B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12,
Application Dilution: WB: 1:500, IHC: 1:100-1:200, FC: 1:100-1:200
Specificity: This antibody detects endogenous levels of CD19 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of CD19.
MW: ~ 61, 95 kDa
Swis Prot.: P15391
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG1. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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