CD19 polyclonal, anti-human, mouse, rat
€378.00
In stock
SKU
250585
Catalog Nr.: 250585
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cellular Antigens, Receptors and Channels
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation.
Alternate Names: B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, Leu-12, CD19 antigen, CD19
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P15391
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD-19.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Seo JH et al. 2016. Int J Mol Med. 37(5): 1221-8. PMID 27035741.
[2] Chang C. et al. 2015. IBC Pharmaceuticals, Inc. Patent US20140099254.
[2] Borrione P et al. 2013. Dept. Health Science. University of Rome. Blood Transfus. Doi: 10.2450/2013.0275-12.
[3] Cristofanilli M et al. 2014. Exp Neurol. 261: 620-32. PMID 25111532.
[4] Soliman H. et al. 2015. Breast Cancer. 7: 389-397. PMID 26719725.
[5] Liu L-F. et al. 2015. Diabetologia. PMID 25952479.
Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation.
Alternate Names: B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, Leu-12, CD19 antigen, CD19
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P15391
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD-19.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Seo JH et al. 2016. Int J Mol Med. 37(5): 1221-8. PMID 27035741.
[2] Chang C. et al. 2015. IBC Pharmaceuticals, Inc. Patent US20140099254.
[2] Borrione P et al. 2013. Dept. Health Science. University of Rome. Blood Transfus. Doi: 10.2450/2013.0275-12.
[3] Cristofanilli M et al. 2014. Exp Neurol. 261: 620-32. PMID 25111532.
[4] Soliman H. et al. 2015. Breast Cancer. 7: 389-397. PMID 26719725.
[5] Liu L-F. et al. 2015. Diabetologia. PMID 25952479.
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