CD2 (clone EBS-CD-002), anti-human

Source:
A BALB/c mouse was immunized with human Sézary T cells.
Fusion partner: NS-1.



Specifications:
CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen presenting cells, as well as between cytolytic effectors and target cells.

Species reactivity:
Positive: human.

Applications:
Characterization of leukemia and lymphoma.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: -
Western blot: +

Positive control: 293T or Jurkat cells. Lymph node and tonsil.

References:
- Thurlow PJ, et al., Transplantation36: 293-298 (1983).
- Kozarsky KF, et al, Cell Immunol150: 235-246 (1993).
- Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 342-352.
- Bell GM, J Immunol155: 2805-2807 (1995).