CD20 (clone HI47) PE, anti-human
€390.00
In stock
SKU
251064
Catalog Nr.: 251064
Size: 2 ml
Isotype: mouse IgG3
Applications: FC
Size: 2 ml
Isotype: mouse IgG3
Applications: FC
Protein Family: Cellular Antigens
Pathway and Disease: Cancers, Immune System
Description:
The CD20 (HI47) antibody recognizes a 33-37 kDa type-III non-glycosylated phosphoprotein spanning the cell membrane four times therefore called TM4. CD20 antigen is expressed on pre-B cells, resting/activated B cells and corresponding neoplastic B cells, but is absent from plasma cells. CD20 regulates B lymphocyte activation and proliferation. The antibody also reacts with several dendritic, endothelial, epithelial, activated T cells and macrophages. The antibody stains 8-16% of normal peripheral blood lymphocytes. The CD20 (HI47) Antibody inhibits B lymphocyte activation and proliferation.
Alternate Names: B-lymphocyte antigen CD20, Membrane-spanning 4-domains subfamily A member 1, B-lymphocyte surface antigen B1, Leu-16, Bp35, MS4A1, CD20
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P11836, NP_690605
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Yang XF., et al. 1990. Shanghai J. of Immunology. 10(2):65
Yang XF., et al. 1991 Chinese J. Immunology. 7(1): 21.
Knapp W., et al. Eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P:798, 1078 Oxford University Press, New York
Schlossman S., et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P:491, 505, 2003 Oxford University Press, New York.
Pathway and Disease: Cancers, Immune System
Description:
The CD20 (HI47) antibody recognizes a 33-37 kDa type-III non-glycosylated phosphoprotein spanning the cell membrane four times therefore called TM4. CD20 antigen is expressed on pre-B cells, resting/activated B cells and corresponding neoplastic B cells, but is absent from plasma cells. CD20 regulates B lymphocyte activation and proliferation. The antibody also reacts with several dendritic, endothelial, epithelial, activated T cells and macrophages. The antibody stains 8-16% of normal peripheral blood lymphocytes. The CD20 (HI47) Antibody inhibits B lymphocyte activation and proliferation.
Alternate Names: B-lymphocyte antigen CD20, Membrane-spanning 4-domains subfamily A member 1, B-lymphocyte surface antigen B1, Leu-16, Bp35, MS4A1, CD20
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P11836, NP_690605
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Yang XF., et al. 1990. Shanghai J. of Immunology. 10(2):65
Yang XF., et al. 1991 Chinese J. Immunology. 7(1): 21.
Knapp W., et al. Eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P:798, 1078 Oxford University Press, New York
Schlossman S., et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P:491, 505, 2003 Oxford University Press, New York.
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