CD21 (clone HI21a) FITC, anti-human
€390.00
In stock
SKU
251010
Catalog Nr.: 251010
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Protein Family: Cellular Antigens
Pathway and Disease: Immune System
Description:
The CD21 (HI21a) Antibody recognizes a 145-kDa type-I transmembrane glycoprotein which is a receptor for C3d complement (CR2) and Epstein-Barr virus (EBVR). CD21 antigen is mainly expressed on mature B cells, follicular dendritic cells, and weakly expressed on subsets of normal thymocytes and T cells, and certain epithelial cells. CD21 is absent from NK cells, granulocytes and monocytes. Some cell populations of B-CLL and T-ALL also express CD21 antigen. CD21 may play a role in B cell activation and proliferation.
Alternate Names: CD21, Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CR2, C3DR
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P20023
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System
Description:
The CD21 (HI21a) Antibody recognizes a 145-kDa type-I transmembrane glycoprotein which is a receptor for C3d complement (CR2) and Epstein-Barr virus (EBVR). CD21 antigen is mainly expressed on mature B cells, follicular dendritic cells, and weakly expressed on subsets of normal thymocytes and T cells, and certain epithelial cells. CD21 is absent from NK cells, granulocytes and monocytes. Some cell populations of B-CLL and T-ALL also express CD21 antigen. CD21 may play a role in B cell activation and proliferation.
Alternate Names: CD21, Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CR2, C3DR
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P20023
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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