CD221 (IGF1R) polyclonal, anti-human, mouse, rat

Protein Family: Cellular Antigens, Enzymes, Protein Kinases, Receptors and Channels

Pathway and Disease: Cancers, Cell Communication, Nervous and Sensory Systems

Description:
IGF1R binds insulin-like growth factor 1 (IGF1) with high affinity and IGF2 with low affinity. The receptor has a tyrosine protein kinase activity necessary for the activation of the IGF1-stimulated downstream signaling cascade.

Alternate Names: Insulin-like growth factor I receptor, CD221 antigen, IGF-I receptor, IGF1R

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: P08069, NP_000866

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human IGF1R.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.