CD225 polyclonal, anti-human, mouse, rat, bovine

Protein Family: Cellular Antigens

Pathway and Disease: Signaling Molecules and Interaction, Immune System, Infectious Diseases

Description:
Interferon-induced transmembrane protein 1 (CD225) is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. CD225 plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. CD225 is implicated in the control of cell growth. CD225 is a component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Alternate Names: IFITM1, interferon-induced transmembrane protein 1, CD225, Interferon-inducible protein 9-27, Interferon-induced protein 17, Leu-13 antigen, IFI17 

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P13164

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD225.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.