CD243 (P-glycoprotein) polyclonal, anti-human, mouse, rat
€362.00
In stock
SKU
250820
Catalog Nr.: 250820
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cellular Antigens, Transporters
Pathway and Disease: Cancers, Membrane Transport
Description:
P-glycoprotein 1 (multidrug resistance protein 1, MDR1) is an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Genetic variation in MDR1 are the cause for patients who do not respond to drug treatment. In mouse, the MDR gene family includes three or more related but distinct cellular genes. MDR1A is also called P-glycoprotein 3.
Alternate Names: Multidrug resistance protein 1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243, ABCB1, MDR1, PGY1, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, P-glycoprotein 3, ABCB1a, MDR1A, PGY3, Multidrug resistance protein 3, Abcb4, Mdr3, Pgy-3
Application Notes: Cat. 250820 recognizes human P-glycoprotein 1 (MDR1) and mouse P-glycoprotein 3 (MDR1A). E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P21447
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse P-glycoprotein 3.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
McCaffrey G et al. 2012. Pre-clinical Systematic Reviews. 122(5):200-213. PMID# 22716933
Pathway and Disease: Cancers, Membrane Transport
Description:
P-glycoprotein 1 (multidrug resistance protein 1, MDR1) is an energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Genetic variation in MDR1 are the cause for patients who do not respond to drug treatment. In mouse, the MDR gene family includes three or more related but distinct cellular genes. MDR1A is also called P-glycoprotein 3.
Alternate Names: Multidrug resistance protein 1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243, ABCB1, MDR1, PGY1, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, P-glycoprotein 3, ABCB1a, MDR1A, PGY3, Multidrug resistance protein 3, Abcb4, Mdr3, Pgy-3
Application Notes: Cat. 250820 recognizes human P-glycoprotein 1 (MDR1) and mouse P-glycoprotein 3 (MDR1A). E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P21447
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse P-glycoprotein 3.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
McCaffrey G et al. 2012. Pre-clinical Systematic Reviews. 122(5):200-213. PMID# 22716933
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