CD244 (SLAMF4) polyclonal, anti-human, mouse, rat
€347.00
In stock
SKU
254451
Catalog Nr.: 254451
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
Alternate Names: Signaling lymphocytic activation molecule family member 4, natural killer cell receptor 2B4, NKR2B4, 2B4, NAIL, NMRK, CD244
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_1160135
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human SLAMF4.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
Alternate Names: Signaling lymphocytic activation molecule family member 4, natural killer cell receptor 2B4, NKR2B4, 2B4, NAIL, NMRK, CD244
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_1160135
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human SLAMF4.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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