CD25 (clone HI25a), anti-human
€323.00
In stock
SKU
250957
Catalog Nr.: 250957
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Protein Family: Cellular Antigens
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD25 (HI25a) antibody recognizes a 55 kDa type-I transmembrane glycoprotein known as the low-affinity receptor for IL-2 (IL-2Rα). CD25 associates with CD122 (IL-2Rβ, P75) and the common γ Chain-CD132 (IL-2Rγ, P64) to form the high-affinity IL-2R complex. CD25 antigen is expressed on activated T and B lymphocytes, activated macrophages, and adult T-cell leukemia (ATL) cells, but is absent from resting T and B cells. CD25 antigen density is altered by treatment with PHA, ConA and CD3 antibody.
Alternate Names: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL2-RA, IL2-RA, p55, TAC antigen, CD25 antigen, IL2RA
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections and formalin-fixed paraffin-embedded tissues. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P01589, NP_000409
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Tadamitsu K et al. eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD25 (HI25a) antibody recognizes a 55 kDa type-I transmembrane glycoprotein known as the low-affinity receptor for IL-2 (IL-2Rα). CD25 associates with CD122 (IL-2Rβ, P75) and the common γ Chain-CD132 (IL-2Rγ, P64) to form the high-affinity IL-2R complex. CD25 antigen is expressed on activated T and B lymphocytes, activated macrophages, and adult T-cell leukemia (ATL) cells, but is absent from resting T and B cells. CD25 antigen density is altered by treatment with PHA, ConA and CD3 antibody.
Alternate Names: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL2-RA, IL2-RA, p55, TAC antigen, CD25 antigen, IL2RA
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections and formalin-fixed paraffin-embedded tissues. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P01589, NP_000409
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Tadamitsu K et al. eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
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