CD25 polyclonal, anti-human, mouse, rat
€378.00
In stock
SKU
251220
Catalog Nr.: 251220
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytokines, Cellular Antigens, Receptors and Channels, Transporters
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Signal Transduction
Description:
Interleukin-2 receptor subunit alpha (CD25) is a receptor for interleukin-2. CD25 is a non-covalent dimer consisting of an alpha and a beta subunit. CD25 exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Genetic variations in CD25 are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10), a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy.
Alternate Names: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL2-RA, IL2-RA, p55, TAC antigen, CD25 antigen, IL2RA
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P01589; NP_000408
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD25.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Signal Transduction
Description:
Interleukin-2 receptor subunit alpha (CD25) is a receptor for interleukin-2. CD25 is a non-covalent dimer consisting of an alpha and a beta subunit. CD25 exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Genetic variations in CD25 are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10), a multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy.
Alternate Names: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL2-RA, IL2-RA, p55, TAC antigen, CD25 antigen, IL2RA
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P01589; NP_000408
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD25.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review