CD253 (TRAIL) polyclonal, anti-human
€347.00
In stock
SKU
252074
Catalog Nr.: 252074
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytokines, Cellular Antigens
Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death, Immune System
Description:
Tumor necrosis factor ligand superfamily member 10 (TRAIL CD253) is a cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. TRAIL 253 induces apoptosis, and its activity is modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Alternate Names: TRAIL, Apo-2L , TNF-related apoptosis-inducing ligand, Tumor necrosis factor ligand superfamily member 10, Protein TRAIL, Apo-2 ligand, CD253, TNFSF10, APO2L
Application Notes: E: 1:10,000-1:40,000; WB: 1:100-1:500; IHC: 1:50-1:200
Accession No.: P50591
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TRAIL CD253.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death, Immune System
Description:
Tumor necrosis factor ligand superfamily member 10 (TRAIL CD253) is a cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. TRAIL 253 induces apoptosis, and its activity is modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Alternate Names: TRAIL, Apo-2L , TNF-related apoptosis-inducing ligand, Tumor necrosis factor ligand superfamily member 10, Protein TRAIL, Apo-2 ligand, CD253, TNFSF10, APO2L
Application Notes: E: 1:10,000-1:40,000; WB: 1:100-1:500; IHC: 1:50-1:200
Accession No.: P50591
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TRAIL CD253.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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