CD271 (NGFR) (clone 2F1C2), anti-human
€394.00
In stock
SKU
252943
Catalog Nr.: 252943
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, FC, IF
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, FC, IF
Protein Family: Receptors and Channels
Pathway and Disease: Cell Growth and Death, Development and Behavior, Nervous and Sensory Systems, Signal Transduction, Signaling Molecules and Interaction
Description:
NGFR (p75NTR) is a low affinity neurotrophin receptor. NGFR binds neurotrophins including NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and NT-4. Nerve growth factor (NGF) is important for the development, differentation, survival of a variety of neuronal and non-neuronal cells. NGF action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75 NTR (NGFR). NGFR is a TNF-R superfamily member, reported to mediate NGF-induced apoptosis.
Alternate Names: Tumor necrosis factor receptor superfamily member 16, Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, CD271, NGFR, TNFRSF16
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P08138
Antigen: Purified recombinant fragment of human NGFR expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cell Growth and Death, Development and Behavior, Nervous and Sensory Systems, Signal Transduction, Signaling Molecules and Interaction
Description:
NGFR (p75NTR) is a low affinity neurotrophin receptor. NGFR binds neurotrophins including NGF, brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and NT-4. Nerve growth factor (NGF) is important for the development, differentation, survival of a variety of neuronal and non-neuronal cells. NGF action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75 NTR (NGFR). NGFR is a TNF-R superfamily member, reported to mediate NGF-induced apoptosis.
Alternate Names: Tumor necrosis factor receptor superfamily member 16, Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, CD271, NGFR, TNFRSF16
Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P08138
Antigen: Purified recombinant fragment of human NGFR expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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