CD272 polyclonal, anti-human, mouse, rat

Protein Family: Cellular Antigens, Receptors and Channels

Pathway and Disease: Immune System

Description:
B- and T-lymphocyte attenuator (BTLA or CD272) is a lymphocyte inhibitory receptor which inhibits lymphocytes during the immune response. CD272 is not expressed by naïve T-cells but is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. CD272 is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).

Alternate Names: B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, CD272, BTLA

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q7Z6A9

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD272.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.