CD3 polyclonal, anti-human, mouse, rat, rabbit, pig, bovine
€378.00
In stock
SKU
250588
Catalog Nr.: 250588
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cellular Antigens, Receptors and Channels
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD3 antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. NK cells also express the CD3 antigen in the cytoplasm.
Alternate Names: T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4, CD3, T3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P07766
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD3 epsilon.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Can G et al. 2016. Clin Res Hepatol Gastroenterol. 40(4): 504-16. PMID 26823039.
[2] Karaca T et al. 2015. Iran J Basic Med Sci. 18(4): 370-379. PMID 26019800.
[3] Karaca T et al. 2011. Allergologia Immunopathologia. 40(6): 357-361. PMID 22115572.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD3 antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. NK cells also express the CD3 antigen in the cytoplasm.
Alternate Names: T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4, CD3, T3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P07766
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD3 epsilon.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Can G et al. 2016. Clin Res Hepatol Gastroenterol. 40(4): 504-16. PMID 26823039.
[2] Karaca T et al. 2015. Iran J Basic Med Sci. 18(4): 370-379. PMID 26019800.
[3] Karaca T et al. 2011. Allergologia Immunopathologia. 40(6): 357-361. PMID 22115572.
| Is Featured? | No |
|---|
Write Your Own Review
Related Products
Check items to add to the cart or
