CD3 polyclonal FITC, anti-human, mouse, rat, rabbit, pig, bovine

Protein Family: Cellular Antigens, Receptors and Channels

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
The CD3 antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. NK cells also express the CD3 antigen in the cytoplasm.

Alternate Names: T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4, CD3, T3

Application Notes: IF: 1:20-1:100; Ex: 490-495 nm, Em: 520-530 nm

Accession No.: P07766

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD3 epsilon.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.