CD309 (VEGFR2) (clone FLK-6), anti-human

Protein Family: Enzymes, Protein Kinases, Receptors and Channels, Transporters

Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Cell Communication

Description:
VEGFR-2 (Vascular endothelial growth factor receptor 2) is a tyrosine-protein kinase and receptor for VEGF or VEGFC. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In HIV-1 infection cases, VEGFR2 interaction with extracellular viral Tat protein enhances angiogenesis in Kaposi's sarcoma lesions.

Alternate Names: Vascular endothelial growth factor receptor 2, VEGFR-2, Protein-tyrosine kinase receptor Flk-1, Kinase insert domain receptor, CD309, KDR, FLK1, VEGFR2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P35968

Antigen: Recombinant human extracellular domain of VEGFR2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.