CD31 (clone TP1/15) FITC, anti-human RUO

This antibody reacts with the CD31-antigen, which is expressed on human thrombocytes. The monoclonal antibody reacts with thrombocytes, monocytes/macrophages and granulocytes. In immunohistology the monoclonal antibody reacts with endothelial cells histiocytes (weak) and glomeruli. The antigen is localized at regions of cell-cell contacts and may function as an adhesion molecule, mediating adhesion between leucocytes and endothelial cells, leucocytes and platelets, and endothelial cells with other endothelial cells.

Recomended usage
CD31, clone TP1/15, is a mAb intended for the identification/ enumeration of PECAM-1 by FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.