CD324 (CDH1)(clone 7A2), anti-human
€429.00
In stock
SKU
253086
Catalog Nr.: 253086
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Cancers, Cell Communication, Signaling Molecules and Interaction
Description:
CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.
Alternate Names: Epithelial cadherin, Uvomorulin, Cadherin-1, CAM 120/80, CD324 antigen, CDH1, CDHE, UVO
Application Notes: WB: 1:500-1:2000
Accession No.: P12830, NP_004351
Antigen: Purified recombinant fragment of human CDH1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Signaling Molecules and Interaction
Description:
CDH1 (Cadherin-1) is a cell adhesion protein, member of the cadherin family. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers.
Alternate Names: Epithelial cadherin, Uvomorulin, Cadherin-1, CAM 120/80, CD324 antigen, CDH1, CDHE, UVO
Application Notes: WB: 1:500-1:2000
Accession No.: P12830, NP_004351
Antigen: Purified recombinant fragment of human CDH1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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