CD326 (EpCAM) (clone VU-1D9) APC, anti-human RUO
€0.00
In stock
SKU
IS-326A-100T
Specificity:
The VU-1D9 monoclonal antibody reacts with the human CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas is a type I transmembrane protein containing six disulfide bridges and one THYRO domain.
Recomended usage:
CD326, clone VU-1D9, is a mAb intended for the identification of bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.
Application: FCM
Storage Temperature: Store in the dark at 2-8 °C
Shelf life: Each reagent is stable until the expiration date shown on the bottle label when stored as directed (at least, one year)
The VU-1D9 monoclonal antibody reacts with the human CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas is a type I transmembrane protein containing six disulfide bridges and one THYRO domain.
Recomended usage:
CD326, clone VU-1D9, is a mAb intended for the identification of bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.
Application: FCM
Storage Temperature: Store in the dark at 2-8 °C
Shelf life: Each reagent is stable until the expiration date shown on the bottle label when stored as directed (at least, one year)
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