CD33 (clone 2B7C12), anti-human
€407.00
In stock
SKU
252815
Catalog Nr.: 252815
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Immune System
Description:
CD33 is a 67kDa type-I transmembrane glycoprotein. It is a cell adhesion molecule expressed mainly on monocytes, granulocytes (weakly), myeloid progenitors and mast cells, but not on lymphocytes, platelets, erythrocytes and hematopoietic stem cells. CD33 antigen is a useful marker for the diagnosis of non lymphoblastic leukemias and also for distinguishing myelogenous leukemia cells from lymphoid leukemia cells. The CD33 antigen is early expressed in the cytoplasm (cyCD33) and then on the cell membrane (mCD33) of the myeloblasts.
Alternate Names: CD33, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67, SIGLEC3
Application Notes: E: 1:5,000-10,000; WB: 1:500-1:2000
Accession No.: P20138
Antigen: Purified recombinant fragment of CD33 (aa48-258) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System
Description:
CD33 is a 67kDa type-I transmembrane glycoprotein. It is a cell adhesion molecule expressed mainly on monocytes, granulocytes (weakly), myeloid progenitors and mast cells, but not on lymphocytes, platelets, erythrocytes and hematopoietic stem cells. CD33 antigen is a useful marker for the diagnosis of non lymphoblastic leukemias and also for distinguishing myelogenous leukemia cells from lymphoid leukemia cells. The CD33 antigen is early expressed in the cytoplasm (cyCD33) and then on the cell membrane (mCD33) of the myeloblasts.
Alternate Names: CD33, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67, SIGLEC3
Application Notes: E: 1:5,000-10,000; WB: 1:500-1:2000
Accession No.: P20138
Antigen: Purified recombinant fragment of CD33 (aa48-258) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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