CD38 (clone 6E12D), anti-human
€394.00
In stock
SKU
252939
Catalog Nr.: 252939
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Protein Family: CAM Ligands, Cellular Antigens, Enzymes
Pathway and Disease: Cofactor and Vitamin Metabolism, Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD38 is a 45-kDa single chain type-II transmembrane glycoprotein. It is expressed on thymocytes, activated T and B cells, hematopoietic progenitors and terminally differentiated B cells/plasma cells (at high levels). CD38 antigen is also present on monocytes, dendritic cells, NK cells and some epithelial cells. CD38 is a NAD glycohydrolase and is a regulator of cell activation and proliferation, and also involved in adhesion between human lymphocytes and endothelial cells.
Alternate Names: CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000;
Accession No.: P28907
Antigen: Purified recombinant fragment of human CD38 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Gupta P. et al 2010. Blood. 116(17):3258-67. doi: 10.1182. PMID#20628151. Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 humanized antibodies correlate with enhanced toxicity to B-cell lymphomas and leukemias.
Pathway and Disease: Cofactor and Vitamin Metabolism, Immune System, Signal Transduction, Signaling Molecules and Interaction
Description:
CD38 is a 45-kDa single chain type-II transmembrane glycoprotein. It is expressed on thymocytes, activated T and B cells, hematopoietic progenitors and terminally differentiated B cells/plasma cells (at high levels). CD38 antigen is also present on monocytes, dendritic cells, NK cells and some epithelial cells. CD38 is a NAD glycohydrolase and is a regulator of cell activation and proliferation, and also involved in adhesion between human lymphocytes and endothelial cells.
Alternate Names: CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000;
Accession No.: P28907
Antigen: Purified recombinant fragment of human CD38 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Gupta P. et al 2010. Blood. 116(17):3258-67. doi: 10.1182. PMID#20628151. Multiple signaling pathways induced by hexavalent, monospecific, anti-CD20 and hexavalent, bispecific, anti-CD20/CD22 humanized antibodies correlate with enhanced toxicity to B-cell lymphomas and leukemias.
| Is Featured? | No |
|---|
Write Your Own Review