CD4 (clone 8G1B12), anti-human, mouse, rat
€396.00
In stock
SKU
253281
Catalog Nr.: 253281
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Receptors and Channels
Pathway and Disease: Immune System, Infectious Diseases
Description:
CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
Alternate Names: CD4, CD4 antigen, CD4 receptor
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P01730
Antigen: 193-aa recombinant protein within the N-term region of human CD4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System, Infectious Diseases
Description:
CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
Alternate Names: CD4, CD4 antigen, CD4 receptor
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P01730
Antigen: 193-aa recombinant protein within the N-term region of human CD4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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