CD4 (clone HIT4a) PE, anti-human
€390.00
In stock
SKU
251048
Catalog Nr.: 251048
Size: 2 ml
Isotype: mouse IgG2b
Applications: FC
Size: 2 ml
Isotype: mouse IgG2b
Applications: FC
Protein Family: Cellular Antigens, Cell Adhesion Molecules
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD4 (HIT4a) Antibody recognizes a 55 kDa type-I single-chain transmembrane glycoprotein. CD4 antigen is a coreceptor for HLA class II molecule and HIV (human immunodeficiency virus), which is present on 35-50% of peripheral blood lymphocytes-T helper/inducer (Th/Ti), 70-80% of thymocytes and in low density on the peripheral blood monocytes and tissue macrophages. Th/Ti helps Ig production by B lymphocytes by enhancing maturation and increasing effectiveness of cytotoxic CD8 T cells.
Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P01730
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD4 (HIT4a) Antibody recognizes a 55 kDa type-I single-chain transmembrane glycoprotein. CD4 antigen is a coreceptor for HLA class II molecule and HIV (human immunodeficiency virus), which is present on 35-50% of peripheral blood lymphocytes-T helper/inducer (Th/Ti), 70-80% of thymocytes and in low density on the peripheral blood monocytes and tissue macrophages. Th/Ti helps Ig production by B lymphocytes by enhancing maturation and increasing effectiveness of cytotoxic CD8 T cells.
Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P01730
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
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