CD40 (clone 9G10), anti-human
€429.00
In stock
SKU
252904
Catalog Nr.: 252904
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: IF
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: IF
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Receptors and Channels
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
CD40 is a 48-kDa type-I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. The ligand for CD40 is CD154 (CD40L). CD40 is involved in growth, differentiation, isotype-switching on B cells and rescuing B cells from apoptosis.
Alternate Names: CD40, Tumor necrosis factor receptor superfamily member 5, CD40L receptor, B-cell surface antigen CD40, Bp50, CDw40, TNFRSF5
Application Notes: IF: 1:200-1:1000
Accession No.: P25942
Antigen: Purified recombinant fragment of CD40 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
CD40 is a 48-kDa type-I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. The ligand for CD40 is CD154 (CD40L). CD40 is involved in growth, differentiation, isotype-switching on B cells and rescuing B cells from apoptosis.
Alternate Names: CD40, Tumor necrosis factor receptor superfamily member 5, CD40L receptor, B-cell surface antigen CD40, Bp50, CDw40, TNFRSF5
Application Notes: IF: 1:200-1:1000
Accession No.: P25942
Antigen: Purified recombinant fragment of CD40 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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