CD40 polyclonal, anti-human, mouse, rat
€378.00
In stock
SKU
251840
Catalog Nr.: 251840
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Receptors and Channels, Cell Adhesion Molecules, CAM Ligands, Cellular Antigens
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Infectious Diseases
Description:
CD40 molecule, TNF receptor superfamily member 5 (CD40) is a member of the TNF-receptor superfamily. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Alternate Names: CD40, Tumor necrosis factor receptor superfamily member 5, CD40L receptor, B-cell surface antigen CD40, Bp50, CDw40, TNFRSF5
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P27512
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD40.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zou X-L et al. 2014. Int J Mol Sci. 15: 6592-6608. PMID# 24747594.
Pathway and Disease: Signaling Molecules and Interaction, Immune System, Infectious Diseases
Description:
CD40 molecule, TNF receptor superfamily member 5 (CD40) is a member of the TNF-receptor superfamily. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Alternate Names: CD40, Tumor necrosis factor receptor superfamily member 5, CD40L receptor, B-cell surface antigen CD40, Bp50, CDw40, TNFRSF5
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P27512
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD40.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zou X-L et al. 2014. Int J Mol Sci. 15: 6592-6608. PMID# 24747594.
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