CD44 (clone 8E2F3), anti-human, mouse
€377.00
In stock
SKU
252831
Catalog Nr.: 252831
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, IF, FC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, IF, FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Proteoglycans, Receptors and Channels
Pathway and Disease: Cancers, Cell Communication, Immune System, Signaling Molecules and Interaction
Description:
CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). The HCELL glycoform was originally discovered on human hematopoietic stem cells and leukemic blasts, and was subsequently identified on cancer cells.
Alternate Names: CD44, CD44 antigen, Phagocytic glycoprotein I, PGP-I, HUTCH-I, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Application Notes: E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P16070
Antigen: Purified recombinant fragment of human CD44 (628-699) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Immune System, Signaling Molecules and Interaction
Description:
CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). The HCELL glycoform was originally discovered on human hematopoietic stem cells and leukemic blasts, and was subsequently identified on cancer cells.
Alternate Names: CD44, CD44 antigen, Phagocytic glycoprotein I, PGP-I, HUTCH-I, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Application Notes: E: 1:10000; WB: 1:500-1:2000; IHC: 1:200-1:1000; IF: 1:200-1:1000; FC: 1:200-1:400
Accession No.: P16070
Antigen: Purified recombinant fragment of human CD44 (628-699) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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