CD44 (clone HI44a), anti-human

Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Proteoglycans, Receptors and Channels

Pathway and Disease: Cancers, Cell Communication, Immune System, Signaling Molecules and Interaction

Description:
The CD44 (HI44a) antibody recognizes a highly glycosylated 80-90 kDa type-I transmembrane cell surface protein, which is the receptor for hyaluronic acid, also called phagocytic glycoprotein-1 (Pgp-1). CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation.

Alternate Names: CD44, CD44 antigen, Phagocytic glycoprotein I, PGP-I, HUTCH-I, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500

Accession No.: P16070

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.