CD44 (clone HI44a) FITC, anti-human
€390.00
In stock
SKU
251024
Catalog Nr.: 251024
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Proteoglycans, Receptors and Channels
Pathway and Disease: Cancers, Cell Communication, Immune System, Signaling Molecules and Interaction
Description:
The CD44 (HI44a) antibody recognizes a highly glycosylated 80-90 kDa type-I transmembrane cell surface protein, which is the receptor for hyaluronic acid, also called phagocytic glycoprotein-1 (Pgp-1). CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation.
Alternate Names: CD44, CD44 antigen, Phagocytic glycoprotein I, PGP-I, HUTCH-I, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P16070
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Immune System, Signaling Molecules and Interaction
Description:
The CD44 (HI44a) antibody recognizes a highly glycosylated 80-90 kDa type-I transmembrane cell surface protein, which is the receptor for hyaluronic acid, also called phagocytic glycoprotein-1 (Pgp-1). CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation.
Alternate Names: CD44, CD44 antigen, Phagocytic glycoprotein I, PGP-I, HUTCH-I, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, CDw44
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P16070
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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