CD49b (clone TEA1/41) APC, anti-human RUO

This antibody reacts with the CD49b-antigen (GPIa or VLA-2 alpha-chain), which can form distinct complexes with either the CD29-antigen (GPIIa or VLA beta-chain), resulting in the VLA-2 (alpha-2 beta- 1) complex, which is expressed on human platelets. The monoclonal antibody reacts with platelets, long-term cultivated T lymphocytes and activated T lymphocytes. In immunohistology the monoclonal antibody reacts with thymocytes, epithelial cells of a variety of tissues, peripheral nerves, fibroblasts, osteoclasts, glomerular mesangium and most non-haemopoietic adherent cell lines.

Recomended usage
CD49b, clone TEA1/41 is a mAb intended for the identification/enumeration of Integrin alpha-2 protein using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.