CD55 (clone HI55a) PE, anti-human
€358.00
In stock
SKU
252280
Catalog Nr.: 252280
Size: 2 ml
Isotype: Mouse IgG2a
Applications: FC
Size: 2 ml
Isotype: Mouse IgG2a
Applications: FC
Protein Family: Cellular Antigens
Pathway and Disease: Immune System, Infectious Diseases, Signaling Molecules and Interaction
Description:
The CD55 (HI55a) antibody recognizes the human cell surface antigen CD55 (complement decay-accelerating factor, DAF), a GPI linked molecule widely expressed on human peripheral blood granulocyte, monocyte, and some lymphocytes and erythrocytes. CD55 recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups during their activation. This interaction interferes with the conversion of C2 and factor B to amplify the complement cascade. CD55 polymorphism is responsible for the Cromer blood group system.
Alternate Names: Complement decay-accelerating factor, CD55, CR, DAF
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08174
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 1% BSA with 0.05% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Infectious Diseases, Signaling Molecules and Interaction
Description:
The CD55 (HI55a) antibody recognizes the human cell surface antigen CD55 (complement decay-accelerating factor, DAF), a GPI linked molecule widely expressed on human peripheral blood granulocyte, monocyte, and some lymphocytes and erythrocytes. CD55 recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups during their activation. This interaction interferes with the conversion of C2 and factor B to amplify the complement cascade. CD55 polymorphism is responsible for the Cromer blood group system.
Alternate Names: Complement decay-accelerating factor, CD55, CR, DAF
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08174
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 1% BSA with 0.05% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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