CD58 (clone HI58a) FITC, anti-human
€390.00
In stock
SKU
251031
Catalog Nr.: 251031
Size: 2 ml
Isotype: mouse IgG1
Applications: FC
Size: 2 ml
Isotype: mouse IgG1
Applications: FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Immune System
Description:
The CD58 (HI58a) antibody recognizes a 55-70 kDa membrane glycoprotein known as the lymphocyte function associated antigen-3 (LFA-3). CD58 antigen has wide distribution over many tissues, both hematopoietic and non-hematopoietic cells, including leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts. There are two isoforms of CD58 antigen: a glycosylphosphatidylinositol (GPI)- anchor form and a transmembrane form. Both forms are expressed on the same cell type, however erythrocytes only have the GPI- anchored isoform. CD58 is an adhesion molecule that binds to CD2 for cell signaling to T cells and NK cells.
Alternate Names: CD58, Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, LFA3
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P19256
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System
Description:
The CD58 (HI58a) antibody recognizes a 55-70 kDa membrane glycoprotein known as the lymphocyte function associated antigen-3 (LFA-3). CD58 antigen has wide distribution over many tissues, both hematopoietic and non-hematopoietic cells, including leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts. There are two isoforms of CD58 antigen: a glycosylphosphatidylinositol (GPI)- anchor form and a transmembrane form. Both forms are expressed on the same cell type, however erythrocytes only have the GPI- anchored isoform. CD58 is an adhesion molecule that binds to CD2 for cell signaling to T cells and NK cells.
Alternate Names: CD58, Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3, LFA3
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P19256
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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