CD59 (clone VJ1/12,2) APC, anti-human RUO

This antibody reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).

Recomended usage
CD59, clone VJ1/12,2 , is a mAb used for the idenfitication of CD59 protein expressed on all hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.