CD62L (clone HI62L), anti-human

Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Glycan Binding Proteins

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
The CD62L (HI62L) antibody recognizes a 76-kDa type-I transmembrane glycoprotein, L- selectin, also called leukocyte endothelial cellular adhesion molecule-1 (LECAM-1). CD62L is expressed on most peripheral blood T cells, B cells, some NK cells, monocytes and neutrophils. CD62L is also expressed on some splenic lymphocytes, bone marrow lymphocytes and myeloid cells, thymocytes and certain hematopoietic malignant cells. CD62L acts as the peripheral lymph node homing receptor, mediates lymphocytes homing to high endothelial venules (HEV) of peripheral lymphoid tissue and leukocytes rolling on activated endothelium at inflammatory sites.

Alternate Names: CD62L, L-Selectin, Lymph node homing receptor, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, TQ1, gp90-MEL, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, CD62 antigen-like family member L, SELL

Application Notes: E: 1:500-1:1,000; FC: 1:200-1:1,000

Accession No.: P14151

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.