CD63 (clone TEA3/18) PE, anti-human RUO

This antibody reacts with the CD63- antigen, which is expressed in platelet lysosomes that is translocated to the platelet surface upon activation with strong agonists. The antigen is also present in most peripheral blood cells (not in erythrocytes) and in many tissues; both surface and cytoplasmatic locations are reported. It has been reported a cellular expression of CD63 in intracellular lysosomal, endosomal and granulate protein, in Weibel Palade bodies of vascular endothelium, in degranulated neutrophils, monocytes, macrophages and endothelium.

Recomended usage
CD63, clone TEA3/18, is a mAb intended for the identification of activated platelets. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.