CD7 (clone HIT7), anti-human
€323.00
In stock
SKU
250940
Catalog Nr.: 250940
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC
Protein Family: Cellular Antigens
Pathway and Disease: Immune System
Description:
The CD7 (HIT7) antibody recognizes a 40 kDa type-I single-chain transmembrane glycoprotein. CD7 antigen is considered as one of the earliest and immature T cell markers that is expressed on all thymocytes, most mature T cells, B-lineage progenitors, NK cells, monocytes (weakly) and some leukemia stem cells capable of multilineage differentiation. CD7 antigen may be considered as a marker of undifferentiated hemopoietic cells capable of giving rise to T, B and myeloid lineage cells under the appropriate microenvironment. CD7 is also present in the majority of T lymphoid leukemia cells and a subset of acute myeloid leukemia (AML) cells. Mature B lymphocytes and granulocytes do not express CD7 antigen.
Alternate Names: T-cell antigen CD7, GP40, T-cell leukemia antigen, TP41, Leu-9, CD7
Application Notes: E: 1:500-1:1,000; FC: 1:200-1:1,000
Accession No.: P09564, NP_006128
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York.
Pathway and Disease: Immune System
Description:
The CD7 (HIT7) antibody recognizes a 40 kDa type-I single-chain transmembrane glycoprotein. CD7 antigen is considered as one of the earliest and immature T cell markers that is expressed on all thymocytes, most mature T cells, B-lineage progenitors, NK cells, monocytes (weakly) and some leukemia stem cells capable of multilineage differentiation. CD7 antigen may be considered as a marker of undifferentiated hemopoietic cells capable of giving rise to T, B and myeloid lineage cells under the appropriate microenvironment. CD7 is also present in the majority of T lymphoid leukemia cells and a subset of acute myeloid leukemia (AML) cells. Mature B lymphocytes and granulocytes do not express CD7 antigen.
Alternate Names: T-cell antigen CD7, GP40, T-cell leukemia antigen, TP41, Leu-9, CD7
Application Notes: E: 1:500-1:1,000; FC: 1:200-1:1,000
Accession No.: P09564, NP_006128
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York.
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