CD8 (clone RAVB3), anti-human
€297.00
In stock
SKU
252600
Catalog Nr.: 252600
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, FC
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
CD8 T cell surface antigen is either a homodimer of alpha chains or a heterodimer of alpha and beta chains. CD8 is a type I membrane co-receptor molecule binding to MHC class I. CD8 antigen is expressed on human cytotoxic/suppressor T-cells, human NK cell subset, and a cortical thymocyte subset. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
Alternate Names: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a antigen, CD8a, MAL
Application Notes: E: 1:10000-1:20000; FC: 1:200-1:400
Accession No.: P01732
Antigen: Purified recombinant fragment of human CD8 expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
CD8 T cell surface antigen is either a homodimer of alpha chains or a heterodimer of alpha and beta chains. CD8 is a type I membrane co-receptor molecule binding to MHC class I. CD8 antigen is expressed on human cytotoxic/suppressor T-cells, human NK cell subset, and a cortical thymocyte subset. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
Alternate Names: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a antigen, CD8a, MAL
Application Notes: E: 1:10000-1:20000; FC: 1:200-1:400
Accession No.: P01732
Antigen: Purified recombinant fragment of human CD8 expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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