CD80 (B7.1) (clone CD80-99), anti-human

Source:
A BALB/c mouse was immunized with recombinant full length CD80.
Fusion partner: NS-1.



Specifications:
CD80 is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is included by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

Species reactivity:
Positive: human.

Applications:
Demonstration of CD80.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +

Positive control: Tonsil or lymph node.

References:
- Peach, R.J., et al. J. Biol. Chem. 270: 21181-21187(1995).
- Fargeas, C.A., et al. J. Exp. Med.182: 667-675(1995).