CD81 (TAPA-1) (clone 1.3.3.22), anti-human

Source:
A BALB/c mouse was immunized with B-cell line derived from a Burkitt lymphoma.
Fusion partner: NS-1.



Specifications:
1.3.3.22 Reacts with human CD81 (TAPA-1), a 24 kDa member of the TM4 superfamily of proteins with four transmembrane domains. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. CD81 can associate with CD37 and/or CD53, or on the surface of B-cells with CD19, CD21 and/or MHC class II molecules. 1.3.3.22 Was clustered at the VIth WLDA.

Species reactivity:
Positive: human.

Applications:
1.3.3.22 is excellent for CD81 staining in paraffin sections and for immunofluorescence and flow cytometry.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Citrate
Western blot: +

Positive control: Ramos cells, human tonsil.

References:
- Kishimoto T. et al., eds. Leukocyte Typing VI, Garland Publishing, Inc, New York and London, (1997).