CD86 (clone ), anti-human, rat, cynomolgus monkey

Background:
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

Alternative Name:
Activation B7-2 antigen 3, Activation B7-2 antigen, Activation B72 antigen, B lymphocyte activation antigen B7 2, B lymphocyte activation antigen B72, B-lymphocyte activation antigen B7-2 2, B-lymphocyte activation antigen B7-2, B7 2, B7 2 antigen, B7, B7-2, B7.2, B70, B72 antigen, BU63, CD 86, CD28 antigen ligand 2 2, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD28LG2, CD86, CD86 antigen, 2, CD86 antigen, CD86 molecule, CD86, CLS1, CTLA 4 counter recep

Application Dilution: WB: 1:1000-1:2000, IHC/ICC/IF: 1:50-1:200, FC: 1:50-1:100

Specificity: This antibody detects endogenous levels of CD86 and does not cross-react with related proteins.

Immunogen:
Recombinant antibody.

MW: ~ 37, 70 kDa

Swis Prot.: P42081

Purification & Purity:
Protein A affinity purified

Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.