CD89 (clone MIP7c), anti-human
€339.00
In stock
SKU
250124
Catalog Nr.: 250124
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, FC, B
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, FC, B
Protein Family: Cellular Antigens, Receptors and Channels
Pathway and Disease: Immune System
Description:
The CD89 antigen (Fc alpha receptor I) binds to the Fc region of immunoglobulins alpha (IgA). CD89 mediates several immune functions including cytokine production. CD89 consists of a membrane-distal Ig-like extracellular domain (EC1), a membrane-proximal Ig-like extracellular domain (EC2), a transmembrane region, and a short cytoplasmic tail. This antibody recognizes the EC1 domain of human CD89 by flow cytometry and also inhibits CD89 functions.
Alternate Names: Immunoglobulin alpha Fc receptor, IgA Fc receptor, CD89 antigen, FCAR, CD89
Application Notes: E: 1 ug/ml; B: 4 ug/4 x 10e5 cells for blocking CD89 functions; FC: 10 ug/ml. This antibody recognizes the EC1 domain of Fc alpha-RI extracellular region.
Accession No.: P24071
Antigen: Soluble human CD89 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zhang, W et al. 2000. Clin. Exp. Immunol. 121: 106-111. PMID # 10886246.
Pathway and Disease: Immune System
Description:
The CD89 antigen (Fc alpha receptor I) binds to the Fc region of immunoglobulins alpha (IgA). CD89 mediates several immune functions including cytokine production. CD89 consists of a membrane-distal Ig-like extracellular domain (EC1), a membrane-proximal Ig-like extracellular domain (EC2), a transmembrane region, and a short cytoplasmic tail. This antibody recognizes the EC1 domain of human CD89 by flow cytometry and also inhibits CD89 functions.
Alternate Names: Immunoglobulin alpha Fc receptor, IgA Fc receptor, CD89 antigen, FCAR, CD89
Application Notes: E: 1 ug/ml; B: 4 ug/4 x 10e5 cells for blocking CD89 functions; FC: 10 ug/ml. This antibody recognizes the EC1 domain of Fc alpha-RI extracellular region.
Accession No.: P24071
Antigen: Soluble human CD89 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Zhang, W et al. 2000. Clin. Exp. Immunol. 121: 106-111. PMID # 10886246.
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