Cell Structure Labeling Immunocytochemistry Kit

Background:
Some of the major cell structures that form eukaryotic cells include a plasma membrane, cytoskeleton, nuclear envelope, cell junctional complexes and extracellular adhesion sites. The cytoskeleton includes actin filaments, microtubules, and intermediate filaments. These major cytoskeletal filaments are important for cell motility, cell adhesion, and cell morphology. Focal adhesions are protein complexes localized to the inner side of the plasma membrane at sites of adhesion. These complexes are important for adhesion to other cells and to the extracellular matrix. Paxillin is an important component of focal adhesions, while β-catenin is an important part of cell-cell junctions. The nucleus is formed from intermediate filament proteins that form a nuclear envelope. Nucleoporin p62 is an important protein in the nuclear pores that facilitate protein transport across the nuclear envelope.

Buffer/Storage:
Mouse monoclonal and secondary reagents are supplied in phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year.