CHRDL1 (clone ), anti-human, mouse, rat
€388.00
In stock
SKU
MB0127
Background:
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
Alternative Name:
Neuralin-1 Neurogenesin-1 Ventroptin, CHL, VOPT, NRLN1, dA141H5.1
Application Dilution: WB: 1:1000, ICC: 1:300
Specificity: CHRDL1 mAb detects endogenous levels of CHRDL1 protein.
Immunogen:
Recombinant full length Human CHRDL1.
MW: Predicted band size: 57kDa , Observed band size: 57kDa
Swis Prot.: Q9BU40
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
Alternative Name:
Neuralin-1 Neurogenesin-1 Ventroptin, CHL, VOPT, NRLN1, dA141H5.1
Application Dilution: WB: 1:1000, ICC: 1:300
Specificity: CHRDL1 mAb detects endogenous levels of CHRDL1 protein.
Immunogen:
Recombinant full length Human CHRDL1.
MW: Predicted band size: 57kDa , Observed band size: 57kDa
Swis Prot.: Q9BU40
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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