CHRNA7 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction

Description:
Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7) is a receptor for acetylcholine. Upon binding of acetylcholine, CHRNA7 an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.

Alternate Names: N-AChR alpha 7, Nicotinic acetylcholine receptor alpha 7, Neuronal acetylcholine receptor subunit alpha-7, NACRA7, Neuronal nicotinic acetylcholine receptor alpha 7, CHRNA7, NACHRA7

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P36544

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CHRNA7.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.