CHUK (clone 3G12H9), anti-human

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Signal Transduction, Cell Growth and Death

Description:
CHUK (Conserved helix-loop-helix ubiquitous kinase) is a member of the serine/threonine protein kinase family. CHUK is a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Alternate Names: Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B inhibitor kinase alpha, NFKBIKA, Transcription factor 16, TCF-16, IKKA, TCF16, CHUK

Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000;

Accession No.: O15111

Antigen: Purified recombinant fragment of human CHUK expressed in E. coli.

Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.